连花清瘟胶囊治疗季节性流感的临床研究

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Abstract Objective Lianhuaqingwen capsules has been used for treatment of influenza A(such as H1N1). To evaluate the efficacy and safety of Lianhuaqingwen(LHQW) for treatment of influenza. Methods This study was conducted during the influenza epdemic season from December 2010 to April 2014 in this hospital. 793 adults (451 wind-heat syndrome and 342 wind-cold syndrome) were enrolled into the study. All subjects were randomized into either the LHQW or AFWA group. The median duration of fever, alleviation of symptoms and adverse events were evaluated among four groups. Results The cumulative alleviation proportion in LHQW group was significantly higher than that in the AFWA group. The median duration of the fever was shorter in the LHQW group than in the AFWA group[(2.1±0.9) d vs( 3.3±1.2) d, P＜0.01]. In the wind-heat syndrome population, influenza-like symptoms were alleviatied more effiicently than in the wind-cold syndrome individuals. Adverse events were similar in both the LHQW group and the AFWA group. The main adverse events following LHQW were gastrointestinal symptoms, such as diarrhea. Conclusion LHQW is effective and well tolerated in treatment of influenza infection.

Key words： influenza Lianhuaqingwen capsules wind-heat syndrome wind-cold syndrome

Received: 21 January 2014

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R373.13

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	Articles by authors
	DAI Yue-Long
	BAI Hui-Ying
	LIU Jian-Cheng

Cite this article:

DAI Yue-Long,BAI Hui-Ying,LIU Jian-Cheng. Efficacy and safety of Lianhuaqingwen capsules in treatment of influenza[J]. , 2014, 25(8): 800-802.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2014/V25/I8/800

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