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Relationship between TF and lymphangiogenesis in colorectal carcinoma |
HAN Chengxin1, JIA Yuanli1,HEI Yan2, CAI Xiaojun1, and WU Jinhu1 |
1.Department of General Surgery, 2.Department of Ophthalmology,General Hospital of Chinese People’s Armed Police Forces,Beijing 100039, China |
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Abstract Objective To investigate the correlation between tissue factor (TF) and lymphangiogenesis in colorectal cancer. Methods Operation records of resected colorectal cancer and corresponding paraffin block of resected primary tumors from 2011/1/1 to 2012/1/1 in this hospital were collected. By immunohistochemistry, the expression of TF, podoplanin in tumor tissues, and microlymphatic vessel density,were observed,and the microlymphatic vessel density between TF positive and negative expression groups. Results The microlymphatic vessel density in positive TF group(47.23±26.12). was higher than that in negative group(36.77±21.56). Conclusions There is high correlation between TF and microlymphatic vessel density in colorectal cancer.
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Received: 03 June 2014
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