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Factors of cognitive function in patients with carotid artery stenosis |
MENG Hongtao1, LI Zhanning1, HUI Zengqian1,2, HE Junhong1, and WANG Lan1 |
1. Medical Department, Shaanxi Provincial Corps Hospital of Chinese People's Armed Police Force, Xi’an 710054, China; 2. Department of Medicine, Xi'an Jiao Tong University, Xi’an 710061, China |
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Abstract Objective To investigate the factors of cognitive function in patients with carotid artery stenosis and proovide reference for the early identification of cognitive impairment.Methods Clinical data of 116 patients with carotid artery stenosis diagnosed by digital subtraction angiography (DSA) were recruited. The cognitive function was assessed by the Montreal Cognitive Assessment Scale (MoCA). Multivariate analysis was used to screen the influencing factors of cognitive function.Results The mean of total score of MoCA was 19.23±2.52. A total of 72 cases were detected to have cognitive impairment, with a detection rate of 62.1%. Multivariate analysis showed that age (β=-3.71,P=0.02), smoking (β=-2.02,P=0.02), hypertension(β=-2.40,P=0.02), hyperlipemia(β=-2.65,P=0.02), diabetes(β=-3.29,P=0.03) and stenosis degree(β=-4.41,P=0.03) were the influencing factors of cognitive function in patients with carotid stenosis.Conclusions Influencing factors of cognitive function in patients with carotid stenosis may include vascular risk factors and pathological characteristics of stenosis.
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Received: 11 January 2016
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