急性冠脉综合征合并心源性休克术后伴发认知功能障碍的影响因素

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Abstract Objective To explore the correlations between influencing factors of acute coronary syndrome(ACS) due to cardiac shock(CS) and post-operative cognitive dysfunction(POCD).Methods Patients of ACS combined with CS treated in our hospital between July 2014 to January 2016 were enrolled in this study. Basic data on the patients’ general health was recorded. Scores of acute physiology and chronic health evaluation Ⅱ (APACHEⅡ) and intra-aortic balloon pump indicators were collected. Those factors were taken as covariates while whether patients of ACS combined with CS were accompanied by POCD within one week of hospitalization was taken as the dependent variable. Binary logistic regression analysis was performed to identify independent factors.Results Based on inclusion and exclusion criteria, 48 cases of ACS combined with CS were ultimately included, among whom 18 were complicated with POCD in the corresponding period, and 30 had nocognitive dysfunction. Interventions were comparable between the two groups, so was the basic data except for age and levels of education. Binary logistics regression analysis showed that the level of education,use of IABP and dexmedetomidine were independent protective factors while age, NSE, the time taken to recanalize blood vessels after chest pain, and sudden drop of blood pressure in reducing counter pulsation frequency were independent risk factors.Conclusions Clinicians should be alert to these influencing factors, conduct timely screening and implement interventions as soon as possible in order to effectively prevent the occurrence of POCD, improve clinical outcomes of patients with ACS combined with CS.

Key words： cardiac shock acute coronary syndromes cognitive dysfunction

Received: 19 April 2017

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R541.64

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	Articles by authors
	CHENG Huafeng
	DUAN Xin
	and WANG Wei

Cite this article:

CHENG Huafeng,DUAN Xin,and WANG Wei. Correlations between acute coronary syndrome combined with cardiac shock and post-operative cognitive dysfunction[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2017, 28(7): 690-693.

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http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2017/V28/I7/690

[1]	李小鹰. 心血管急症救治——心源性休克的诊断和处理[J].中国循环杂志,2013,185(5):486-487.
[2]	Goldberg R J, Spencer F A, Gore J M, et al. Thirty-year trends(1975 to 2005) in the magnitude of management and hospital death rates associated with cardiogenic shock in patients with acute myocardial infarction: a population-based perspective[J].Circulation,2009,119(11):1211-1219.
[3]	魏宇淼,陈芬,杨仕俊,等.现阶段心血管重症病房心源性休克患者的住院存活情况分析[J].重庆医学, 2015,26(2):3644-3646.
[4]	边红. 慢性心功能衰竭与认知障碍[J].中华老年医学杂志,2014,33(5):565-568.
[5]	Lee C N, Ko D, Suh Y W, et al. Cognitive functions and stereopsis in patients with Parkinson's disease and Alzheimer’s disease using 3-dimensional television: a case controlled trial[J]. PLoS One, 2015, 10(3):e0123229.
[6]	孟宏涛, 李战宁, 惠增骞,等. 影响颈动脉狭窄患者认知功能的因素调查[J]. 武警医学, 2016, 27(6):577-579.
[7]	中国防治认知功能障碍专家共识专家组.中国防治认知功能障碍专家共识[J].中华内科杂志,2006,45(2): 171-173.
[8]	O’Connor R E, Brady W, Brooks S C, et al. Acute coronary syndromes: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care[J]. Circulation, 2010,122(18):787-817.
[9]	中华医学会心血管病学分会, 中华心血管病杂志编辑委员会. 急性心力衰竭诊断和治疗指南[J].中华心血管病杂志,2010,38(2):195-206.
[10]	张庆成, 汪承炜, 梁桂娟,等. 急性心肌梗死心源性休克冠脉血栓抽吸并支架置入术的疗效及其安全性[J]. 武警医学, 2015, 26(8):765-767.
[11]	朱文佳, 高中宝,杨磊, 等. 蒙特利尔认知评估量表筛查轻度认知功能障碍分界值的研究[J].中华老年心脑血管病杂志,2012,14(5):500-503.
[12]	Dalrymple-Alford J C, MacAskill M R, Nakas C T, et al. The MoCA: well-suited screen for cognitive impairment in Parkinson disease[J].Neurology,2010,75(3):1717-1725.
[13]	吕裕霞,李卉,闫赋琴,等. 高压氧对阿尔茨海默病模型小鼠认知功能的影响[J]. 武警医学, 2016, 27(11): 1126-1128.