Investigation of hyperuricemia and its risk factors in young male officers and soldiers
LIU Changxin1, SHI Xiaoping2, WANG Lingyun3, ZHANG Baohua4, GAO Yueming4, JING Cui4, ZHAO Mingxing4
1. Lishilu Outpatient Department, Central Medical Branch of PLA General Hospital, Beijing, 100045,China; 2. Nephrology Department, Fuxing Hospital Affiliated to Capital Medical University; 3. Anningzhuang Outpatient Department, Central Medical Branch of PLA General Hospital, Beijing 100045,China; 4. Department of Health Care, the Second Medical Center of PLA General Hospital, Beijing 100853,China
Abstract：Objective To investigate the prevalence of hyperuricemia (HUA) in young males and to explore its related risk factors. Methods A total of 335 young male officers and soldiers of a PLA Unit aged 18 to 29 who participated in physical examination in May 2024 were divided into HUA group and a control group according to serum uric acid value. General information and laboratory examination were collected, questionnaire survey was conducted on diet and exercise status to compare the differences between the two groups, and risk factors were analyzed by logistics regression. Results A total of 116 cases (34.63%) suffered from HUA. In HUA group, age, BMI, waist circumference (WC), diastolic blood pressure (DBP), gamma-glutaminase transferase (GGT), alanine aminotransferase (ALT), prevalence of fatty liver, and consumption of thickened gravy≥twice a week and red meat≥120 g per day were all higher than those in control group, while urinary specific gravity and glomerular filtration rate (GFR) were lower than those in control group, with statistically significant difference (P＜0.05). Pearson correlation analysis showed that BMI, WC, and DBP were positively correlated with HUA (P<0.05), while GFR was negatively correlated with HUA (P<0.05). Multivariate analysis showed that BMI≥24 kg/m2 (OR=1.812, 95%CI 1.115-2.944, P=0.016), DBP≥80 mmHg (OR=2.410, 95%CI 1.078-5.388, P=0.032),GFR＜90 ml/(min·1.73 m2)(OR=7.592, 95%CI 1.588-36.291, P=0.011), and red meat consumption≥120 g per day (OR=1.921, 95%CI 1.120-3.294, P=0.018) were risk factors of HUA. Conclusions Body weight, blood pressure, renal function, and red meat consumption should be paid more attention for young men to reduce the risk of HUA.
刘长鑫, 石晓萍, 王凌云, 张保华, 高月明, 井翠, 赵明星. 某部青年男性官兵高尿酸血症调查及其危险因素分析[J]. 武警医学, 2025, 36(2): 97-101.
LIU Changxin, SHI Xiaoping, WANG Lingyun, ZHANG Baohua, GAO Yueming, JING Cui, ZHAO Mingxing. Investigation of hyperuricemia and its risk factors in young male officers and soldiers. Med. J. Chin. Peop. Armed Poli. Forc., 2025, 36(2): 97-101.
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