Effect of epidural ketamine on shivering in transurethral resection of prostate
CHENG Gansheng,SHAO Qingzhu,MAO Tian,PAN Mian
Department of Anesthesiology, Nanjing Branch Hospital of Jiangsu Provincial Corps Hospital of Chinese People’s Armed Police Forces, Nanjing 210028， China
Abstract：Objective To investigate the effect of epidural ketamine on shivering in transurethral resection of the prostate (TURP). Methods Ninety-three male patients scheduled for TURP under epidural anesthesia were enrolled in this study. Patients were randomly divided into three groups. Group 1 consisted of 31 patients who received epidural 0.75% ropivacaine, group 2 consisted of 32 patients who received epidural ketamine (0.2 mg/kg) in addition to 0.75% ropivacaine, and group 3 consisted of 30 patients who received epidural ketamine (0.4 mg/kg) in addition to 0.75% ropivacaine. Shivering and side effects such as hypotension, bradycardia, nausea, and hallucination were recorded during the anesthesia and for 2 hours while in the postanesthetic recovery room. Results Shivering was statistically more frequent in group 1 than in the other groups and the incidences of side effects such as hypotension, bradycardia, and nausea were significantly higher in group 1 than in the other groups (P<0.05). The incidence of sedation was significantly higher in group 3 than in the other groups (P<0.05). Conclusions In patients who undergo TURP under epidural anesthesia, the prophylactic use of low-dose epidural ketamine would be helpful in preventing any adverse effects, including shivering.
2013, Vol. 24 
