Characteristics of hypokalemic paralysis secondary to type 1 renal tubular acidosis in primary sjogren syndrome
LIU Peng1,WANG Qian2,and PU Chuanqiang3
1.Department of VIP Neurology, Navy General Hospital of PLA, Beijing 100048, China; 2.Department of Emergency, General Hospital of Chinese People’s Armed Police Force, Beijing100039, China; 3. Department of Neurology, General Hospital of PLA, Beijing 100853, China
Abstract:Objective To explore the clinical features of hypokalemic paralysis secondary to type 1 renal tubular acidosis in primary sjogren syndrome.Methods We retrospectively studied eighteen cases of hypokalemic paralysis secondary to type 1 renal tubular acidosis in primary sjogren syndrome.Results The clinical manifestations of hypokalemic paralysis secondary to type 1 renal tubular acidosis preceded the development of sicca syndrome in eleven cases of primary sjogren syndrome. In the other seven cases, the prodromal symptoms were oral dryness (xerostomia) and dryness of eyes (kerato conjunctivitis sicca). All the eighteen cases had hypokalemic paralysis. Among the ten cases of bone disease, nine had osteoporosis, and one had osteomalacia.Conclusions Patients with hypokalemic paralysis secondary to renal tubular acidosis in primary sjogren syndrome have typical clinical features and early diagnosis can lead to proper treatment .
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