Abstract：Objective To investigate the factors related to blockage of catheter drainage or inadequate drainage for malignant pleural effusion(MPE).Methods One hundred and sixty-one cases of malignant pleural effusion with catheter drainage treated in our hospital between November 2015 and December 2017 were selected. According to the patency of the drainage process, the patients were divided into two groups: the drainage patency group and the blockage or poor drainage group. Information about the two groups was collected, including gender, age, time of catheterization, pleural effusion and catheter status. The related factors of blockage of catheter drainage or inadequate drainage for MPE were analyzed.Results There were 32 cases of blockage of catheter drainage or inadequate drainage. There was no statistically significant difference in the incidence of blockage of catheter drainage or inadequate drainage between patients who were different in sex, age, BMI, primary diseases, complications, anticoagulant and targeted drug use or between patients who received thoracic injection and those who did not (P>0.05). A long duration of catheterization, the mouth of the catheter above the liquid surface, cellulosic membrane and blood clots in the effusion, abnormal counts of platelets and positive hydrothorax protein were risk factors for blockage of catheter drainage or inadequate drainage. Logistic regression analysis confirmed that a high level of liquid surface(OR 2.578,95% CI 1.357-4.846), cellulosic membrane and clot (OR 3.218,95% CI 1.651-10.056), and tube-sealing methods (OR 1.689,95% CI 1.427-4.297) were important risk factors (P<0.05) for blockage of catheter drainage or inadequate drainage in case of MPE.Conclusions Catheter blockage is likely to occur during drainage in case of malignant pleural effusion, and the main risk factors include the elevation of the liquid surface, cellulose membrane and blood clots in the effusion and tube-sealing methods. Corresponding interventions can be implemented according to the above risk factors.
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MIAO Kailing, LI Chunyan, and HOU Huiru.. Related factors of blockage of catheter drainage or inadequate drainage for malignant pleural effusion. Med. J. Chin. Peop. Armed Poli. Forc., 2018, 29(9): 857-860.
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