Abstract：Objective To study the patterns and characteristics of adverse reactions induced by asarone injection and to provide reference for rational use of drug by clinician.Methods By retrieving data from domestic databases, we collected literature about cases of ADRs and information about the patients and medication. Life-threatening cases of ADRs were chosen as the severe ADR in this study.Results Among the eighty-five cases of adverse reactions in this study, there were forty-one cases of severe ADRs, accounting for 48.23%. Fifty-four of the patients were under six years old (63.41%), twenty-eight of whom were severe cases of ADRs, making up 68.29%. 90.58% of the adverse reactions occurred within 10 minutes of administration and 80.48% of the cases of severe ADRs took place in less than 5 minutes. The circulation system was damaged by adverse reactions 156 times, accounting for 34.51%, while the respiratory system was impaired 116 times, accounting for 25.66%. Two patients died from futile treatment, one patient lost eyesight after 13 days of treatment, and the remaining eighty-two patients improved after treatment.Conclusions Adverse reactions caused by asarone injection are mainly allergic reactions and related to multiple factors. Severe ADRs can lead to death unless dealt with without delay. Hence, it is recommended that clinicians should monitor and prevent adverse reactions induced by asarone injection.
2018, Vol. 29 
