Curative effect of Shenling Baishu Powder on serum inflammatory cytokines and mental status of elderly patients with stable chronic obstructive pulmonary disease
XU Juanjuan1, LIAN Yufei2, YAN Li2
1.Department of Pharmacy, 2.Department of Respiratory Medicine, Hebei People’s Hospital, Shijiazhuang 050057, China
Abstract：Objective To investigate the curative effect of Shenling Baishu powder combined with respiratory training on serum inflammatory cytokines levels, mental status and cardiac markers of elderly patients with stable chronic obstructive pulmonary disease(COPD). Methods The clinical data of 96 patients with stable COPD treated at Hebei People’s Hospital between January 2016 and August 2017 was retrospectively analyzed. These patients were divided into the control group and treatment group, with 48 cases in each. The control group was treated with western medicines, while the treatment group was additionally given Shenling Baishu powder combined with respiratory training. The mental status, capability of activity, cardiac markers, serum inflammatory cytokines levels, 6-minute walk test and arterial blood gas analysis were observed before and after treatment. Results The total effective rate was 95.83% in the treatment group, compared with 83.33% in the control group (P＜0.05). After one course of treatment, the mental status and ability of activity were improved in both groups (all P＜0.05), especially in the treatment group (P＜0.05). The hs-crp, BNP and results of 6-minute walk test were improved in both groups ( P＜0.05), especially in the treatment group (P＜0.05). PaO2, SaO2 and PaCO2 were also improved in both groups (P＜0.05), especially in the treatment group (P＜0.05). Conclusions Shenling Baishu powder combined with respiratory training can improve the curative effect among elderly patients with stable COPD, reduce levels of serum inflammatory cytokines, and relieve the psychological symptoms of anxiety and depression.
2019, Vol. 30 
