放置胆管支架与儿童ERCP术后胰腺炎的关系

Abstract
Figure/Table
References
Related Citation (15)

Download: PDF (685 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To explore the relationships between bile duct stent placement and post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) in children.Methods Based on pediatric patients in the National Inpatient Sample (NIS) database of the United States, logistic regression accounting was used for survey design while multiple imputation was adopted to study the relationships between biliary stent placement and PEP. Subgroup analysis was conducted according to gender.Results Children with biliary stent placement were at higher risk of PEP than those without (OR: 1.44, 95% CI: 1.05-1.99, P=0.0246). The results of subgroup analysis showed that boys with biliary stent placement were about 1.9 times as vulnerable to PEP as those without (OR: 1.89, 95% CI: 1.08-3.31, P=0.0262), but for female pediatric patients, bile duct stent placement was not found to be associated with PEP.Conclusions Bile duct stent placement is associated with an increased risk of PEP in children. Therefore, when placing bile duct stents in children, clinicians should take preventive measures, discontinue surgery or change surgical approaches to reduce the risk of PEP.

Key words： children endoscopic retrograde cholangiopancreatography bile duct stent placement pancreatitis risk factors

Received: 20 September 2021

ZTFLH:

R657.4

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	ZHU Ronghui
	XU Yetao
	XU Jinfang
	WANG Rui
	WU Shengyong
	CHEN Chenxin
	WU Cheng

Cite this article:

ZHU Ronghui,XU Yetao,XU Jinfang等. Relationships between bile duct stent placement and post-ERCP pancreatitis in children[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2022, 33(2): 98-101.

URL:

http://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR http://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2022/V33/I2/98

[1]	Barakat M T, Cholankeril G, Gugig R, et al. Nationwide evolution of pediatric endoscopic retrograde cholangiopancreatography indications, utilization, and readmissions over time[J]. J Pediatr, 2021, 232: 159-165.e1.
[2]	Smith A C, Dowsett J F, Russell R C, et al. Randomised trial of endoscopic stenting versus surgical bypass in malignant low bileduct obstruction[J]. Lancet, 1994, 344(8938): 1655-1660.
[3]	Rustagi T, Aslanian H R. Endoscopic management of biliary leaks after laparoscopic cholecystectomy[J]. J Clin Gastroenterol, 2014, 48(8): 674-678.
[4]	Mercier C, Pioche M, Albuisson E, et al. Safety of endoscopic retrograde cholangiopancreatography in the pediatric population: a multicenter study[J]. Endoscopy, 2021, 53(6): 586-594.
[5]	Felux J, Sturm E, Busch A, et al. ERCP in infants, children and adolescents is feasible and safe: results from a tertiary care center[J].Eur Gastroenterol J, 2017, 5(7): 1024-1029.
[6]	Troendle D M, Abraham O, Huang R, et al. Factors associated with post-ERCP pancreatitis and the effect of pancreatic duct stenting in a pediatric population[J]. Gastrointest Endosc, 2015, 81(6): 1408-1416.
[7]	Liu Q Y, Gugig R, Troendle D M, et al. The roles of endoscopic ultrasound and endoscopic retrograde cholangiopancreatography in the evaluation and treatment of chronic pancreatitis in children: a position paper from the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Pancreas Committee[J]. J Pediatr Gastroenterol Nutr, 2020, 70(5): 681-693.
[8]	Keil R, Snajdauf J, Rygl M, et al. Diagnostic efficacy of ERCP in cholestatic infants and neonates--a retrospective study on a large series[J]. Endoscopy, 2010, 42(2): 121-126.
[9]	Shteyer E, Wengrower D, Benuri-Silbiger I, et al. Endoscopic retrograde cholangiopancreatography in neonatal cholestasis[J]. J Pediatr Gastroenterol Nutr, 2012, 55(2): 142-145.
[10]	Agarwal J, Nageshwar Reddy D, Talukdar R, et al. ERCP in the management of pancreatic diseases in children[J]. Gastrointest Endosc, 2014, 79(2): 271-278.
[11]	Hatlani M A, Kortan P, May G, et al. Wire-guided cannulation versus contrast-guided cannulation in pediatric endoscopic retrograde cholangiopancreatography[J]. Saudi J Gastroenterol, 2015, 21(1): 25-29.
[12]	Wong L L, Tsai H H. Prevention of post-ERCP pancreatitis[J]. World J Gastrointest Pathophysiol, 2014, 5(1): 1-10.
[13]	Wilcox C M, Phadnis M, Varadarajulu S. Biliary stent placement is associated with post-ERCP pancreatitis[J]. Gastrointest Endosc, 2010, 72(3): 546-550.
[14]	Shin S H, So H, Cho S, et al. The number of wire placement in the pancreatic duct and metal biliary stent as risk factors for post-endoscopic retrograde cholangiopancreatography pancreatitis[J]. J Gastroenterol Hepatol, 2020, 35(7): 1201-1207.
[15]	Koseoglu H, Solakoglu T, Basaran M, et al. Risk factors for post-ERCP pancreatitis: it depends on the ERCP indication[J]. Acta Gastroenterol Belg, 2020, 83(4): 598-602.
[16]	Agency for Healthcare Research and Quality Healthcare Cost and Utilization Project(HCUP). Introduction to the HCUP national inpatient sample(NIS)[EB/OL]. (2019-12-05)[2021-06-08].https://www.hcup-us.ahrq.gov/db/nation/nis/NISIntroduction2017.pdf.
[17]	Yadav D, O'Connell M, Papachristou G I. Natural history following the first attack of acute pancreatitis[J]. Am J Gastroenterol, 2012, 107(7): 1096-1103.
[18]	Inamdar S, Berzin T M, Sejpal D V, et al. Pregnancy is a risk factor for pancreatitis after endoscopic retrograde cholangiopancreatography in a national cohort study[J]. Clin Gastroenterol Hepatol, 2016, 14(1): 107-114.
[19]	Mutneja H R, Vohra I, Go A, et al. Temporal trends and mortality of post-ERCP pancreatitis in the United States: a nationwide analysis[J]. Endoscopy, 2021, 53(4): 357-366.
[20]	Cote G A, Kumar N, Ansstas M, et al. Risk of post-ERCP pancreatitis with placement of self-expandable metallic stents[J]. Gastrointest Endosc, 2010, 72(4): 748-754.
[21]	Freeman M L. Pancreatic stents for prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis[J]. Clin Gastroenterol Hepatol, 2007, 5(11): 1354-1365.
[22]	Sofi A A, Nawras A, Alaradi O H, et al. Does endoscopic sphincterotomy reduce the risk of post-endoscopic retrograde cholangiopancreatography pancreatitis after biliary stenting? A systematic review and meta-analysis[J]. Dig Endosc, 2016, 28(4): 394-404.