西帕依固龈液联合富血小板纤维蛋白膜治疗慢性牙周病伴三壁骨缺损的效果

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Abstract Objective To study the effect of Xipayi solid gingiva solution combined with platelet-rich fibrin (PRF) in the treatment of chronic periodontal disease with three-wall bone defect. Methods A total of 98 patients diagnosed with severe periodontal disease and three-wall bone defects were selected from the Stomatology Department of General Hospital of Xinjiang Military Region from June 2021 to January 2023. All the the patients were randomly divided into a study group (n=49) and a control group (n=49) according to random number table method. The control group was treated with guide tissue regeneration (GTR) and artificial bone meal implantation, while the study group was treated with PRF membrane and Sipayi gingival solidifying fluid on the basis of the control group. The changes of periodontal exploration (PD), loss of attachment (CAL), gingival sulcus bleeding index (SBI), gingival plaque index (PLI), the level of intragingival inflammatory factors(TNF-α), interleukin-6 (IL-6), interleukin-10 (IL-10) and the treatment effectiveness were compared between the two groups. Results Compared with the control group, the study group patients had lower levels of PD, CAL, PLI, SBI, IL-6, and TNF-α and increased levels of IL-10. The total effective rate of the study group (95.92%) was significantly higher than that of the control group (79.60%), with statistical significance (P<0.05). Conclusions Xipayi solid gingival fluid combined with PRF can effectively improve the level of serum inflammatory factors and periodontal status in the treatment of chronic periodontal disease accompanied by three-wall bone defect.

Key words： Xipayi solid gingiva solution platelet-rich fibrin membrane chronic periodontitis three-wall bone defect

Received: 11 November 2024

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R781.42

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	Articles by authors
	WANG Jin
	DING Mingqin
	BAO Kun
	HE Yue
	YAN Lei

Cite this article:

WANG Jin,DING Mingqin,BAO Kun等. Effect of Xipayi solid gingival fluid combined with platelet-rich fibrin membrane in treatment of chronic periodontal disease with three-wall bone defect[J]. Med. J. Chin. Peop. Armed Poli. Forc., 2025, 36(4): 306-309.

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https://journal08.magtechjournal.com/Jwk_wjyx/EN/ OR https://journal08.magtechjournal.com/Jwk_wjyx/EN/Y2025/V36/I4/306

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