Clinical study on improving uremia accompanied by intracerebral hemorrhage by using sequential hemodialysis without heparin
AN Shuqiang1,YANG Qian1,CUI Ling1,SHI Changsheng1,JIA Xiaojuan2,and WEI Yajuan3
1.Hebei Provincial Corps Hosptial of Chinese People’s Armed Police Forces, Shijiazhuang 050081,China; 2. Anal fistula Specialized Hospital of zhao County, Hebei province, Shijiazhuang 051530, China; 3. The third Hospital of Beijing Municipal Corps, Chinese People’s Armed Police Forces, Beijing 100039, China
Abstract：Objective To investigate clinical effect of sequential hemodialysis without heparine in treatment and prevention of intracerebral hemorrhage in uremic patients. Methods From this hospital we recruited 40 patients with chronic renal failure and uremia who were randomly divided into 2 groups. Group A underwent sequential hemodialysis without heparin; groups B recieived traditional hemodialysis without heparin. Comparative analysis was made of the correlation among different indexes at 24 hours, 3 days,7 days,and 14 days by detecting matrix metalloproteininase-9(MMP-9),interleukin-8(IL-8), interleukin-10(IL-10). The CT of head was serially performed to calculate the volume of hemorrhage and perihematomal hypodensity; multivariate logistic regression analysis of prognosis on intracerebral hemorrhage was conducted. Results Comparing group A and group B at 7 days and 14 days,there were statistically significant differences in MMP-9, IL-8, IL-10,hemorrhage and perihematomal hypodensity(P<0.05). Multivariate logistic regression analysis showed that heart failure, arrhythmia,and pulmonary infection are the effects of prognosis on intracerebral hemorrhage. Conclusions Treatment of intracerebral hemorrhage in uremic patients using sequential hemodialysis without heparine is safe, effective, and worthy of clinical application.
安书强,杨 倩,崔 玲,史长生,贾晓娟,魏雅娟. 无肝素序贯血液透析改善尿毒症合并脑出血的疗效观察[J]. , 2014, 25(2): 176-178.
AN Shuqiang,YANG Qian,CUI Ling,SHI Changsheng,JIA Xiaojuan,and WEI Yajuan. Clinical study on improving uremia accompanied by intracerebral hemorrhage by using sequential hemodialysis without heparin. , 2014, 25(2): 176-178.
2014, Vol. 25 
