Abstract：Objective To make reasonable choices of the clinical antibiotics and provide reference for clinical anti-infection treatment according to the data of pathogen distribution and drug-resistance in sputum specimens of burn patients after tracheotomy in recent 3 years in this hospital. Methods Totally 375 pathogens were isolated from samples of sputum from 94 burn patients after tracheotomy,from October 2010 to October 2013 in Liaoning Provincal Corps Hospital of Chinese People’s Armed Polices. Distribution and susceptibility of bacteria and fungi were statistically analyzed,to set up a database,describing the distribution of the pathogens and the drug-resistance rate of different types of bacteria,and to investigate the change of drug-resistance of common pathogenic bacteria in the 3 years. Results In 297 strains of pathogens,141 isolates were Gram-positive cocci, accounting for 47.5%;132 isolates were Gram-negative bacilli, accounting for 44.4% and 24 isolates were fungi, accounting for 8.1%.The detection rate of Staphylococcus aureus(SA,141 strains, accounting for 51.6%)was the highest,next was Pseudomonas aeruginosa(PA,76 strains, accounting for 27.8%),and 29 strains of Acinetobacter calcoacetius(AC) were isolated,accounting for 10.6%.The proportion of SA and PA decreased year by year,while the proportion of AC showed increasing trend year by year.Vancomycin was the only active antibiotics against SA, the drug resistance rate was 14.9%,and PA showed high drug-resistance against cephalosporin antibiotics(more than 50%).AC was highly resistant with the drug resistance rate over 80%. Conclusions The pathogens isolated from burn patients with lower respiratory tract infection in recent years in Liaoning Provincal Corps Hospital of Chinese People’s Armed Police are mainly SA,PA and AC.The problem of bacterial resistance is serious,which shows a high drug-resistance rate.
2014, Vol. 25 
