Abstract：Objective To evaluate the applicability of 18F-FDG PET/CT in the positional diagnosis of postoperative infections of open fractures in lower extremities, and its role in debridement surgery.Methods Fifteen patients with suspected chronic local infections following surgeries for traumatic fractures of lower extremities were recruited between July 2018 and June 2019. PET/CT examination was performed one week before debridement. Infection lesions were positioned according to PET/CT images and compared with results of postoperative pathology, microbial culture and PET/CT. The mean SUVmax of bone infections and soft tissue infections was calculated, while the findings of PET/CT and SPECT/CT imaging of one patient were analyzed. The effect of PET/CT-guided debridement was assessed.Results Among the 15 patients, 6 had simple bone infection lesions, 3 had simple soft tissue infection lesions, and the other 6 patients had both bone infection lesions and soft tissue infection lesions. A total of 18 bone infection lesions and 12 soft tissue infection lesions were found by PET/CT. The SUVmax of bone infection lesions was 5.1±3.4, compared with 3.6±2.4 for soft tissue infection lesions. The diagnostic sensitivity of PET/CT for bone infections and soft tissue infections was 94.4% and 83.3% respectively. The sensitivity of PET/CT was higher than that of SPECT/CT imaging. Under the guidance of PET/CT, the cure rate of patients with open fractures in lower extremities after one debridement was 93.3% (14/15).Conclusions The accuracy of 18F-FDG PET/CT in the diagnosis of postoperative infections of open fractures of lower extremities is high, and the effect of guided debridement is reliable.
尹亮, 岳建兰, 黄世明, 张庆, 刘菲, 王秋菊, 林志春. 18F-FDG PET/CT对下肢开放骨折术后感染的定位诊断价值及引导作用[J]. 武警医学, 2021, 32(2): 128-131.
YIN Liang, YUE Jianlan, HUANG Shiming, ZHANG Qing, LIU Fei, WANG Qiuju, Lin Zhichun. Applicability of 18F-FDG PET/CT in patients with suspected local infection after open fractures of lower extremity. Med. J. Chin. Peop. Armed Poli. Forc., 2021, 32(2): 128-131.
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2021, Vol. 32 
