A clinical study of correlation between the pathological characteristics of recurrent laryngeal nerve condition variation in thyroid carcinoma and intraoperative nerve monitoring
LI Chen1, TIAN Wen1, ZANG Yu2, YAO Jing2, and CHEN Lin1
1.Department of General Surgery,General Hospital of PLA, Beijing 100853, China; 2.Department of General Surgery, the First Hospital Affiliated to General Hospital of PLA, Beijing 100048, China
Abstract：Objective To analyze the pathological characteristics that thyroid carcinoma leads to recurrent laryngeal nerve injury and detect effectiveness of intraoperative nerve monitoring, recognize,identify and protect recurrent laryngeal nerve. Methods Clinical data of patients with thyroid cancer undergoing total thyroidectomy with intraoperative nerve monitoring were analyzed retrospectively from March 2012 to March 2014 in this hospital.A classification of variation of recurrent laryngeal nerve was made, based on biological characteristics of tumor,as a biological support for recognizing recurrent laryngeal nerve exactly,protecting recurrent laryngeal nerve effectively. Results 436 nerves were exposed in 240 operations,in which 48 variations (10.76％)were found. Variation was related to biological characteristics of thyroid cancer.The variations were classified into location variation type,form variation type, infiltrative lesions variation type.12,9 and 15 cases were identified in studymental group;3,4 and 5 cases were identified in control group.The rates of identification in both two groups were 36/215 and 12/231, showed significant differences(P＜0.05). Conlusions Variation of recurrent laryngeal nerve is vital and potential factor leading to misrecognizition of recurrent laryngeal nerve and recurrent laryngeal nerve injury.
李 晨，田 文，姚 京，臧 宇，陈 凛. 甲状腺癌喉返神经条件变异的病理学基础与术中神经监测相关性研究[J]. 武警医学, 2016, 27(6): 568-570.
LI Chen, TIAN Wen, ZANG Yu, YAO Jing, and CHEN Lin. A clinical study of correlation between the pathological characteristics of recurrent laryngeal nerve condition variation in thyroid carcinoma and intraoperative nerve monitoring. Med. J. Chin. Peop. Armed Poli. Forc., 2016, 27(6): 568-570.
Chiang F Y, Lu I C, Kuo W R, et al. The mechanism of recurrent laryngeal nerve injury during thyroid surgery the application of intraoperative neuromonitoring [J].Surgery,2008,143(6):743-749.
2016, Vol. 27 
