2型糖尿病伴血脂异常患者外周血白细胞及淋巴细胞的变化与临床意义

摘要
图/表
参考文献
相关文章 (15)

全文: PDF (410 KB) RICH HTML
输出: BibTeX | EndNote (RIS)

摘要目的探讨2型糖尿病伴血脂异常患者白细胞、淋巴细胞及淋白细胞比率的变化与临床意义。方法分别收集2型糖尿病血脂异常225例患者及血脂正常109例的静脉血进行全血细胞分析。结果 (1)白细胞数在2型糖尿病患者血脂异常组[(6.50±1.60) ×10⁹/L]及血脂正常组[(6.30±1.63)×10⁹/L]差异无统计学意义;(2)淋巴细胞数在2型糖尿病血脂异常组[(2.08±0.74)×10⁹/L]高于血脂正常组[(1.89±0.60)×10⁹/L，P=0.012];(3)淋白细胞比率在2型糖尿病血脂异常组(0.32±0.091)高于血脂正常组(0.31±0.089，P=0.016)。结论 2型糖尿病患者血脂异常伴有淋巴细胞数量改变，可能与血脂异常参与某些炎性反应有关。

	服务

	把本文推荐给朋友
	加入我的书架
	加入引用管理器
	E-mail Alert
	RSS
	作者相关文章
	罗丽君
	徐成高
	侍晓云
	王向党

关键词 ：白细胞, 淋巴细胞, 血脂异常, 2型糖尿病, 慢性炎性反应

Abstract：Objective To investigate the change of leukocytes, lymphocytes and ratio of lymphocytes and the clinical significance in type 2 diabetic patients with dyslipidemia. Methods We collected venous blood from 225 type 2 diabetes patients with dyslipidemia and 109 type 2 diabetes patients with normal lipid,then analyzed difference in blood routine between the two groups. Results (1)The leukocyte count in type 2 diabetes patients with dyslipidemia was[(6.50±1.60)×10⁹/L] and in type 2 diabetes with normal lipid was[(6.30±1.63) ×10⁹/L],the without P value is 0.326( greater than 0.05).statically significant difference.(2)The number of lymphocytes in type 2 diabetes patients with dyslipidemia was[(2.08±0.74)×10⁹/L] and in type 2 diabetes patients with normal lipid was[(1.89±0.60)×10⁹/L,P=0.012],the P value is 0.012 (less than 0.05).(3)The leukocyte tlymphocyte ratio in type 2 diabetes patients with dyslipidemia was(0.32±0.091) and in type 2 diabetes psstients with normal lipid was(0.31±0.089).the P value is0.016 ( less than 0.05).In the two groups,the lymphocyte cell count and leukocyted lymphocyte ratio has statically significant difference Conclusions In patients with type 2 diabetes ,dyslipidemia causes change in the number of lymphocytes and may beengaged in certain inflammatory reaction.

Key words： leukocytes lymphocytes dyslipidemia type 2 diabetes chronic inflammation

收稿日期: 2015-12-11

ZTFLH:

R589.2

通讯作者: 王向党,E-mail:wangxiangdangwj@163.com

作者简介: 罗丽君，硕士研究生。

引用本文:

罗丽君，徐成高，侍晓云，王向党. 2型糖尿病伴血脂异常患者外周血白细胞及淋巴细胞的变化与临床意义[J]. 武警医学, 2016, 27(5): 447-448. LUO Lijun,XU Chenggao,SHI Xiaoyun, and WANG Xiangdang. Changes and clinical significance of leukocytes and lymphocytes in patients with type 2 diabetes and dyslipidemia. Med. J. Chin. Peop. Armed Poli. Forc., 2016, 27(5): 447-448.

链接本文:

http://journal08.magtechjournal.com/Jwk_wjyx/CN/ 或 http://journal08.magtechjournal.com/Jwk_wjyx/CN/Y2016/V27/I5/447

[1]	刘志民,刘子毓.代谢综合征研究现状及展望[J]. 中华老年心脑血管病杂志,2015,17(4):337-338.
[2]	虎静,雷涛.血脂紊乱与骨质疏松关系的研究进展[J]. 中国骨质疏松杂志,2014,20(6): 337-338.
[3]	Suzan M. Hyperlipidemia in rheumatoid arthritis patients in Saudi Arabia[J]. Saudi Med,2015,36(6):685-691.
[4]	Leila G H, Faramarz Z,Fatemeh H, et al. The Association Between Hyperlipidemia and Periodontal Infection[J]. Iran Red Crescent Med,2014, 16(12): e6577.
[5]	Shehab M. Non-alcoholic fatty liver disease: The diagnosis and management[J]. World J Hepatol,2015,7(6):846-858.
[6]	American Diabetes Association. Standards of medical care in diabetes—2014[J]. Diabetes Care,2014,37(Suppl 1):S14-S80.
[7]	贺斌,陈剑,程金山,等. 2型糖尿病患者外周血白细胞计数与尿白蛋白相关性的分析[J].中国药科学杂志,2012,9(17):58-60.
[8]	迟林,李昊森,许晓风,等.2型糖尿病患者外周血淋巴细胞亚群及Treg细胞检测及临床应用[J].山东医药杂志,2011,51(40):87-89.
[9]	王小林,明军,王永红,等. 白细胞总数及分类与血脂异常的相关性观察[J]. 中国老年学杂志, 2011,3(31):391-393.
[10]	Mehta J L, Li D Y. Inflammation in is chemic heart disease: response to tissue Injury orapathogenetic villain[J].CardiovascRes, 1999,43(2):291-299.