Abstract: The construction of Shanghai global S&T innovation center needs the coordination of industrial knowledge bases and institutions environment. The paper draws the following conclusions through studying their coordination. Firstly, three economic factors which are reform of economic institution, building of market institution and macro-control of government provide flexible institutions for the development of analytic knowledge base, and they are advantageous for construction of Shanghai global S&T innovation center. Shanghai-style culture and white-collar culture in Shanghai social culture institution have positive and negative influence. Shanghai organization scale and ownership structure is matched with its type of industrial knowledge bases, however, location innovation networks of foreign economies need to be strengthen.

Key words: global S&, T innovation center