Abstract: Using the Chinese provincial data, this study establishes the index systems of economic characteristics and analyzes the effect of intellectual property protection on regional economic growth based on the TVP-VAR (Time-Varying Perimeters Vector Auto Regression) Model. The paper discusses the causal relationship and the equilibrium between intellectual property protection and regional economic growth through dynamic regressions. The results show that intellectual property protection, in the developed areas of China, accelerates both regional economic growth and the innovation ability, while inhibits technological innovation capacity in the less and moderately developed regions.