Abstract: Under the background of "mass entrepreneurship and innovation", entrepreneurial performance has become an important issue of academic concern. However, the initial failure rate of entrepreneurship is very high, the research on the factors of re-entrepreneurship and its impact mechanism is relatively lagging behind. Analyzing multiple re-entrepreneurship cases, factors of the re-entrepreneurship performance was extracted. The multi-level hierarchical structure model of the factors of the re-entrepreneurial performance is constructed based on the ISM. The guarantee factor, the key factor and the direct factor of the performance of re-entrepreneurship are clarified. This paper makes up the blank of the systematic research on the re-entrepreneurship performance, which is a supplement for the theory. The study also gives some enlightenments to improve the performance of re-entrepreneurship:(1) support re-entrepreneurship and perfect the corresponding intermediary service system.(2) strengthen the guidance of public opinion, create a "fault tolerant" entrepreneurial atmosphere.(3) for entrepreneurs, it is necessary to have a dream of entrepreneurship and openness.(4) it is very important to manage organizational forgetfulness, and knowledge management ability is of great importance to re-entrepreneurship performance.