Abstract: Clarifying the role of government intervention in the technological development of regional strategic emerging industries is of great significance to the high-quality development of China's economy and innovation-driven development. For the relationship between government intervention and the evolution of urban technological paths, this paper argues that regional knowledge base and innovation origin ability play an important role in it, and examines it from both theoretical and empirical aspects.Theoretically, by constructing a mediated moderation model, it demonstrates that the government intervention effect on the technological paths is affected by the moderation mechanism of the local knowledge base, and innovation origin ability plays a partly mediating role. This model expands the analytical framework for the impact of government intervention on technological paths. Empirically, based on the invention patent data of strategic emerging industries in 139 cities in China from 2010 to 2020, it tests the effect and internal mechanism of government intervention on urban technological development paths and estimates the size of the direct effect and the mediation effect. And for the first time, referring to the innovation radiation and science and technology governance connotation of the innovation origin ability, this research improves its measuring method, and uses the centrality of the patent transfer network to describe the innovation origin ability to highlight its innovation radiation effect. The study finds that government intervention promotes the development of technological paths of strategic emerging industries in cities, and the city's knowledge base plays a positive moderating role; compared with the stage of technological path-creation without comparative advantage, government intervention can have a more significant impact on the stage of path maintenance that already has a comparative advantage; innovation origin ability plays a partly mediating role between government intervention and technological paths, and the mediating effect mainly depends on the first half of the process, and part of the moderating effect of knowledge base is achieved through the innovation origin ability. In terms of policy, putting forward a new model in which government intervention needs to be closely integrated with the regional knowledge base and strengthen the construction of regional innovation origin ability, promoting the organic combination of government intervention and market mechanism in the evolution of technological paths. This paper has important reference significance for the government to use the regional knowledge base and enhance the innovation origin ability to promote the evolution of technological paths, and to promote the high-quality development of China's strategic emerging industries.

摘要： 厘清政府干预在区域战略性新兴产业技术发展中的作用，对中国经济高质量发展和创新驱动发展具有重要意义。本文通过构建以技术知识基础为调节和以创新策源能力为中介的有中介的调节模型，利用2010-2020年中国139个城市的战略性新兴产业发明专利数据，实证检验了地方政府干预对城市技术发展路径的影响效应及内在机制。研究发现，地方政府干预促进城市战略性新兴产业技术路径的发展作用的发挥，显著依赖城市技术知识基础的正向调节作用；创新策源能力在政府干预和技术发展路径之间具有部分中介渠道作用，且创新策源能力的中介效应大小受到城市技术知识基础的正向调节。政策上主张政府干预偏向需要紧密结合区域的知识基础，并通过加强区域创新策源能力的质量建设以促进城市技术路径发展的模式。