Abstract: As an inheritor and important representative figure of the J. D. Bernal the founder of science of science, the renowned crystallographer Alan Lindsay Mackay has a profound understanding of the relationship between science and power, building upon Bernal's systematic thinking about science. His scientific research is primarily focused on the field of crystallography, yet his academic interests extend to the realms of science of science and the history of science. Mackay transcends the microscopic study of crystal structures to encompass the macroscopic impact of science on human affairs. He sought connections between disciplines, with a particular focus on the advancement of science and its interconnections with other fields. He showed a profound interest in studying the social functions of science, as well as its organizational structures and social relationships. This article delves deeply into Mackay's life, career, scientific writings, and academic activities, revealing his contemplation on the relationship between science and power against the backdrop of an in-depth analysis of the relationships between science and the political, social, and economic spheres. It begins with an overview of Mackay's early life and education, highlighting the influence of J. D. Bernal that led him to become one of the most distinguished representatives of scientific discovery and political radicalism in the field of crystallography at Birkbeck, University of London. Continuing on, the article further discusses his illustrious professional career, highlighting his contributions to crystallography and his pioneering work, which have demonstrated his outstanding accomplishments as an eminent and visionary crystallographer. The article then focuses on Mackay's academic interests beyond crystallography, including his explorations in the fields of science of science and the history of science. It uncovers thought-provoking perspectives on maintaining the necessary tension between science and politics, advocating for the use of scientific power in social construction, and emphasizing the regulation of science in economic development. His contemplation of the intricate interplay between science and power holds significant enlightening implications for the field of science and technology governance. The governance framework proposed in this article is constructed based on Mackay's "science and power" thought, analyzing the interests and visions of various governance stakeholders, the balancing processes of conflicts, and the outcomes of these balances. It calls for governance stakeholders to not only need consensus, inclusiveness, respect, epistemological trust, collaboration, participation, openness, and decentralization but also to take preventive measures and reform systems to maintain a dynamic balance. The framework emphasizes the multifaceted role of science in shaping the social structures and power dynamics of modern society. Inspired by Mackay's thoughts on "science and power," the science and technology governance mechanism aims to promote scientific innovation, drive high-quality economic growth, maintain social stability, and achieve sustainable development. In conclusion, Mackay has made significant contributions to the development of crystallophysics and has also left a profound mark in the field of science studies. His thought of "science and power" provides guidance for science and technology governance, revealing the complex interrelationships between science and political, social, and economic powers in the governance process, which is essential for understanding the role of science in modern society.

摘要： 作为科学学奠基人贝尔纳的学生，世界著名晶体物理学家马凯对科学与权力有着深刻的认识。他的科学研究主要集中在晶体物理学领域，但他的学术兴趣也延伸到科学学和科学史等领域。文章从马凯的生平、职业生涯、科学著作和科学活动入手，挖掘他在深入考察科学与政治、社会和经济之间关联的基础上对科学与权力关系的思考。他对科学与权力之间复杂互动关系的思考对于科技治理领域富有启发意义。因此以马凯“科学与权力”思想为治理指南构建了科技治理的框架。