Abstract: Abstract: The previous study on cost stickiness mostly focused on its influencing factors, while the exploration of its economic consequences was less, and the cost stickiness was regarded as a disadvantageous factor. Based on resource-based theory and self-organization theory, this paper takes R&D innovation input as the starting point, and concludes that the cost stickiness imposes the demand of resource adjustment on innovation input, and also provides surplus resources support for innovation input, which has a positive impact on R&D investment. In view of this, this paper examines the relationship between cost stickiness and R&D innovation investment in Chinese manufacturing listed firms in 2010-2015. It is found that cost stickiness has a positive effect on R&D investment. The ownership structure and management characteristics have a moderating effect on the above relationship. The dynamics of environment has a contingency effect on the relationship between cost stickiness and firm R&D investment, which affects the ownership structure and the regulation of the role of management characteristics. This result provides a new perspective for the study of the positive economic consequences of cost stickiness and the influencing factors of R&D innovation.