Abstract: The paper reveals how post-merger integration mode impact acquirer’s knowledge spillover capacity of overseas M&As by enterprises in emerging economies, and how global network position of the acquiring firm mediates this effect. Building on organizational behavior, network, resource orchestration theory, we suggest that the effect between integration mode and network position, depends on resource similarity and complementarity of acquirer and target firm. Using structural equation modelling and bootstrap test, the hypotheses are tested by drawing on a sample of 102 technology-sourcing overseas M&As by Chinese listed manufacture companies. The result shows that acquirers in emerging countries are not able to increase knowledge spillover capacity unless they choose the right post-merger integration mode, including business integration and brand harmonization; We also find the relationship between integration and knowledge spillover is channelled through centrality and structural holes of acquirer in global innovation network. Overall, our study contributes the network view of post-merger integration and knowledge spillover, and shed light on the critical role of post-merger integration mode in the competitive advantage theory of latecomer firms in emerging countries.