Abstract: Silicon Valley is recognized as a synonym for innovation and growth, and it is currently one of global disruptive innovation centers in spotlight. Meanwhile, Apple, Intel, Google and other relevant enterprises in Silicon Valley have become industrial leaders. What explains the persistence of disruptive innovation in Silicon Valley? Combined with the actual needs and research gaps, the case study method is used to explain the code of disruptive innovation through the enterprises’ innovation ecosystem in Silicon Valley. The article first reviews the origins of Silicon Valley and describes the innovation trajectory led by Silicon Valley enterprises. Secondly, it focuses on the analysis of the basic characteristics of typical disruptive innovations of Silicon Valley enterprises, and extracts the common drivers to realize these disruptive innovations. The results show that :(1) building a new and powerful enterprise innovation ecosystem is an important carrier to promote silicon valley enterprises from "late entrant" to "disrupter"; (2) Embedding platforming thinking and modular logic is the key to enhance the uniqueness of silicon Valley's enterprise innovation ecosystem. In the end, some management enlightenments are condensed to provide references for Chinese enterprises that are actively exploring disruptive innovation.