Abstract: In the process of vigorously promoting the development of strategic emerging industries by the central government, the response behavior and effectiveness of local governments have received much attention, but opinions are divergent. From the perspective of multiple institutional logics, the study analyzes the mechanism, type and effect of the government's response to the central government's new energy vehicle promotion and application policies in nine cities in the the Pearl River Delta. The study found that in the process of the promotion and application of new energy vehicles, the incompatibility of the central government logic, local government logic, market logic and other multiple institutional logic and the heterogeneity of local attributes, especially the heterogeneity of local resources and capabilities, under the interaction, the governments of nine cities in the the Pearl River Delta have gradually formed three different response strategies, namely, "pilot", "support", and "auxiliary" strategies; The differentiated response behavior of local governments has not only achieved their respective goals of new energy vehicle promotion and application and the development of new energy vehicle industry, but also promoted the rapid formation of new energy vehicle industry clusters in the the Pearl River Delta with the "leader" as the core and the "auxiliary" and "supporter" as the radiation. The study provides a new analytical approach based on the perspective of multiple institutional logics to explain the heterogeneity and effectiveness of local government response behavior, and also provides a reference for the implementation of "effective government, effective market".