Abstract: The knowledge service is the key driving force of innovation, how does knowledge service transform into innovation performance is still an important and unsolved problems. This paper uses the case study method of grounded theory code selection, Choose1 research and development service institutions and 4 small and medium-sized manufacturing enterprises interactive case as the object of study, the study found: (1) knowledge service includes four elements: innovation planning, demand management, team building and Process specification; (2) a value process includes: value consensus, value symbiosis, value share and win-win; (3) Under the promoting of the innovation leader, there is a interaction between the value contents and knowledge service to create a process, to jointly promote the knowledge service into the innovation performance.