Abstract: The paper analyses the impact of openness of technological innovation on the international competitiveness of Chinese manufacturing industries, some hypothesis have also been proposed. In order to test these hypotheses, an econometric model was established, and the panel data comes from Chinese manufacturing industries from the year of 2000 to 2010. The results show that the openness of technological innovation has a positive influence on the international competitiveness of Chinese manufacturing industries, including international market share, international trade competitiveness, revealed comparative advantage and industry export proportion. Moreover, under the highly market competitive environment, Chinese firms with higher human capital quality will get more profit from open innovation.