Abstract: Regional social-cultural trait is the important factor to influnce entrepreneurship, but few research analyse whether this influence is different in different regions. This paper analyses the selected social traits: the social stigma to entrepreneurial failure and the presence of entrepreneurial role models, over entrepreneurial activity levels in rural area and urban area, in eastern rural and mid-western rural. We find that these two factors have significant influnce over entrepreneurial activity in these areas, but the extent of influnce is different. In rural area and urban area, the influnce of entrepreneurial role models has no significant difference, but the social stigma to entrepreneurial failure is significant weaker in rural area than in urban area. The influnce of entrepreneurial role models is significant stonger in eastern rural area than in mid-western rural area, but the social stigma to entrepreneurial failure has no difference between these two areas.