Abstract: Pusztai affair is the blasting fuse to global dispute about the security of GM crops. This affair shows that a three-spiral-authority structure within scientific field —— the induction of the economic interests, the might of the political union and the pressing of the systematized scientific capital，is continuously extruding and destroying the autonomy of science. Only with the aid of “reflexivity”, strengthening the automony of GM crops's research and development, and actively guiding the intervention of external factors in the field of science, can GM crops better serve the development of modern agriculture.