Abstract: Based on network embedded perspective, this paper explored the mechanism of building entrepreneurial ability through academic and industrial network embeddedness, and accessing to growth performance. Then, this research empirically examined the relationships by using structure equation modeling. The results indicated that, Dual entrepreneurial ability that including “innovation explorative ability” and “resource exploitative ability” has become key internal factor for enterprises to utilize network resources effectively. Further research found that the innovation explorative ability has been increased more significantly by structural embeddedness and relational embeddedness, and it also provided more positive effects for growth performance. Moreover, particular creation property of University spin-off companies (USO) and Company Spin-off companies (CSO) has led to obvious different entrepreneurial ability construction mode.