Abstract: It is essential to strengthen university-industry interaction for carrying out the strategy of innovation-driven development. With the perspective of microcosmic body, universities’ researchers, this article identifies three types of channels of university-industry knowledge transfer in China, academic engagement, commercialization and human resource transfer. It constructs a concept frame of university-industry knowledge transfer including three types of factors, individual characteristics, organization atmosphere and external environment. By using the survey data from four industry characteristic universities, this article analyzes what factors impact the anticipating decisions of researchers in China’s university-industry knowledge transfer. The empirical results argue that the insufficiency of institutional supply on the university level is a bottleneck that obstruct university-industry knowledge transfer in China.