Abstract: Interdisciplinarity is a complex and multidimensional concept, so it is difficult to fully describe its’ essential characteristics by a single indicator. Most previous studies have analyzed interdisciplinarity from single dimension, lacking an overall and systematic perspective. In this paper, we decompose, and then integrate the external knowledge integration, internal knowledge convergence and research activity patterns of interdisciplinarity from three different dimensions. Based on publication data of the winners of Derek de Solla Price, a comparative analysis of category integration, knowledge convergence and scientific cooperation are conducted, to explore the differences, adaptability, relations and possible combination of the three different measurement methods. Compared with the single indicator, our measurement from three dimensions can better profile the interdisciplinary characteristics of research object. Such a comprehensive dimension also provides a new perspective of evaluating interdisciplinary research.