Abstract: Technology innovation is the key way to enhance innovation capability and strengthen core competitiveness, which has an important role in the development of regional economies. Based on the perspective of knowledge aggregation, on the basis of analyzing the entropy change and mutation characteristics of technology innovation, this paper makes a metaphorical analysis for the formation mechanism of technology innovation. This paper uses the cusp catastrophe model in catastrophe theory to build the formation mechanism model of technology innovation and chooses internal knowledge as the state variable, negative entropy caused by external knowledge and entropy increases caused by internal knowledge as control variables. Then it analyzes the formation mechanism of technology innovation in depth. The results show that the formation mechanism of technology innovation is composed of three phases: technology innovation inception phase, the formation phase of incremental technology innovation and the formation phase of radical technology innovation. Finally, we put forward relevant strategies to promote the formation of technology innovation from four aspects: building the sharing mechanism of internal knowledge, increasing the introduction of external knowledge, establishing knowledge aggregation mechanism of internal and external knowledge and improving the support system of technology innovation.