Abstract: Reproducibility crisis is the new challenge of current science since 2010. Firstly, there are deny of reproducibility crisis, or no solution to reproducibility crisis, but the new practice of pre-registration could attempt to control reproducibility crisis. Secondly, from the new idea of pre-registration in 2013 to new wave of pre-registration, the development in the six years is extremely quickly, owing to it is approach to the essence of science. Its standard of peer review is exclusively the creativity of idea and reasonability of design of experiment, as well as the whole quality control of research process, including idea creation, experiment design, experiment process and paper writing. Thirdly, pre-registration require the sign between the testing experiment and exploratory experiment, as well as the whole record of the change from idea to experiment result, so as to preventing from publication bias and elevate the reproducibility of experiment. As long as China develop into innovation country and confront with reproducibility crisis, China should begin to the try pre-registration in some Sci-tech Journals, constructing the idea registration and data upload platform, and new peer review model, so as to diminish reproducibility crisis.