Abstract: Innovation subjects make contributions to the developments of technology and economy through exploring and operating technology innovation. Patent licensing is an important means of technology operation which is crucial for the transformation from technology to economy. It is meaningful to understand the patent licensing deeply by analyzing the difference of licensing of different types of innovation subjects to guide the stakeholders to make effective and proper policy. Data on patent licensing from universities, research institutes, enterprises, and individuals in 2018 is used for the empirical analysis of the difference in patent licensing with the method of statistical and regression method. The results show that there are obvious differences in the patent licensing of different types of innovation subjects. Besides, the strategy of exclusive licensing is influenced by the types of innovation subjects, the area of technology, and other variables. In order to improve the quality of the patent licensing and realize the sound development, it is necessary to make specific policies for different types of innovation subjects.