Abstract: During the transition period of China’s economy from cost-driven to technology-driven, technology licensing, as a key approach of technology transference and transformation, plays an increasingly prominent role. Due to the universality of information asymmetry in the technology licensing process, both parties of technology licensing may have the risk of breach of contract due to various subjective and objective factors in the process of contracting, payment, transfer and implementation. dynamic management timely of various default risks is an important demand for technology licensing decision-makers, while solutions and responses to this demand are insufficient in existing research or theories. In this paper, default risks in the key steps of technology licensing are identified; the main risk factors in the licensing process, originating from information asymmetry among technology licensing subjects, are summarized; a quantitative analysis system for technology licensing default risks, based on the risk matrix method, is constructed; and strategies and methods, combined with risk matrix judgment, for dealing with the risks of major technology licensing defaults are proposed. The conclusion and suggestion of this paper can contribute to default risk management practice for stakeholders and decision-makers of technology licensing.