Abstract: The Fifth Plenary Session of the Nineteenth Central Committee of the CPC and the "Outline" of the National "Fourteenth Five-Year Plan" proposed to promote urbanization construction with counties as an important carrier, marking that county areas have gradually become the focus of China's new urbanization development. Since the development of county-level leading industries determines the level of urban and rural economic development and the life quality of residents to a certain extent, meanwhile, improving the level of regional economic development and the life quality of residents is also an inherent requirement for the development of new urbanization, the development of county-level leading industries has become one of the important ways to promote the development of county-level new urbanization. Judging from the development of the 120 demonstration counties of county-level new urbanization selected by the National Development and Reform Commission, the county areas that play a demonstration role in the development of new urbanization have not yet solved the problem of whether there are leading industries. In the areas where the leading industries have been identified at the present stage, the leading industries have a certain driving role in new urbanization, but it is not obvious. To give full play to the role of county-level leading industries in driving new urbanization, county areas can, according to their actual conditions, promote the development of relevant industries through the three stages of agglomeration and large-scale development, improvement and extension of industrial chains, and high-quality development of leading industries in the development of leading industries, connect the key points of new urbanization development, and drive the development of county-level new urbanization. To realize the development of new urbanization driven by county-level leading industries, county areas should pay attention to the role of the leading industries in the development of new urbanization, scientifically determine county-level leading industries, and further put the development of leading industries and new urbanization into one blueprint to conduct unified planning of "multi-plans into one", so as to promote the integrated development of industries and counties. Meanwhile, county areas should not stick to fixed industry and urbanization development models, but should promote the development of industries and urbanization in an innovation-driven direction according to local conditions, and promote the development of county-level new urbanization as a whole.