Abstract: Science and technology ethics is a value criterion and code of conduct, which must be complied in activities of scientific research and technological development. The report of the 20th National Congress of the Communist Party of China proposes to improve the system of scientific and technological innovation. Strengthening the governance of science and technology ethics is an important way to achieve this goal. It is important for sci-tech self-reliance and self-strengthening to strengthen the ethical governance of science and technology. The ethical governance of science and technology in China faces challenges and situations such as enhancing international competitiveness in science and technology, strengthening ethical regulation in emerging technology fields, and balancing scientific and technological innovation with ethical regulation in a reasonable manner. The paper analyzes the following issues exist in the current ethical governance of science and technology in China, that is, policies and regulatory mechanisms are incomplete, ethical review standardization and talents are lacking, scientific and research person and the public and news media are lack of guidance. Finally, the strategies and proposals to strengthen ethical governance of science and technology are advanced. The strategies and proposals can provide some references for formulation of a science-technology ethical governance system which is suitable for Chinese characteristics.