Abstract: Using the principles of interpretive structure model to construct the level hierarchical structure model of factors affecting women’ entrepreneurial performance，and identify clearly that’s basic conditions, key factors, benchmarks and build path.By choosing a typical entrepreneurial failure case to test the conceptual model. The study found：(1)A series of factors about policy support, the level of economic development , entrepreneurial atmosphere, legal guarantee, traditional thinking, family relationships are the basic condition affecting women’ entrepreneurial performance. (2) A series of factors including the entrepreneurial motivation ( pursuit of independence, economic needs, personal achievements), role perception, personality are the driving factors.(3) A series of Intermediary service，industry environment, entry timing will affecting women’ entrepreneurial performance.(4) Personal capital，network capital，venture management，and sustainability innovation capability are the key factors.(5) The building, output, and maintenance of product service and corporate image are the important benchmarks to measure and reflect the level of women’ entrepreneurial performance.