Abstract: In recent years, complex products and systems (CoPS) in China is developing rapidly, risk accidents happened very often at the same time, the theoretical circle should attach great importance to this phenomenon. To open the black box of CoPS innovation risk, based on the stakeholder network evolution perspective, this paper builds risk analysis framework: the stakeholder network, opportunistic behavior and CoPS innovation risk, and analyzes 2002-2016 years of innovation process of the country’s self-reliance program in Gen III nuclear power technology AP1000 SM nuclear power plant unit 2 project. The results show: the innovation network structures are different in different stages of CoPS, the symmetry degree of the system integrator and stakeholders’ right is different; system integrator and stakeholders pursuing right symmetric state is the inner driving force of stakeholder networks evolution in different CoPS innovation phases; when the right of stakeholders is asymmetric, stakeholders are possible to do opportunism behaviors to achieve rights symmetry, the opportunism behaviors are possible to induce CoPS innovation risk.