Abstract: Under the background of global competition, the way for local brand manufacturers to catch up with innovation has become difficult. More and more local brand manufacturers begin to seek new development tracks, trying to reconstruct their competitive advantages and achieve leapfrog development by "changing lanes and overtaking". Based on the typical case of two chip manufacturers, this paper makes an in-depth discussion on how local brand manufacturers can achieve innovation catching-up through continuous "lane-changing". It is found that the realization of the innovation catch-up goal of local brand manufacturers not only requires the "technological change" and "market change" to go hand in hand, but also many "change" links such as cross-border exploration, frontier technology breakthrough and business ecological reconstruction. The study also found that market environment, technological characteristics, institutional supply, as well as strategic response, resource integration, value reconstruction , are important factors driving local brand manufacturers to "changing lanes and overtaking". The findings provide an important reference for the theory application practice of local brand manufacturers and the supply of government system.