Abstract: Knowledge commercialization of university in China has long plagued the field of science and technology and innovation. The newly revised ‘Bayh-Dole Acts ’of China decentralized disposition of commercialization profit to universities to incentive innovation，how universities respond to that is related to the incentive effect of the policy. Using policy text bibliometrics and interview investigation approaches, based on the 113 pieces of policy texts proposed by universities, this paper analyzes the characteristics of the university's policy response to the Chinese version of ‘Bayh-Dole Acts ’ ;The result shows that ,the policy response characteristics are heterogeneous，compared with high-level universities represented by " 985" and " 211" projects, China's local universities are more " positive" in their response to the new ‘Bayh-Dole Acts’， and have higher willingness to looking for technology transfer. Further, this paper put forward the logical basis of incentive policies for the knowledge transfer in Chinese universities. response under the pressure from the " top - down" political-bureaucracy system, and the intrinsic motivation generated based on the mission orientation and self-characteristics of universities, together lead to the heterogeneous characteristics of incentive policies of Chinese universities in response to the newly revised ‘Bayh-Dole Acts’. the inherent autonomy of universities should be highly considered in the knowledge commercialization incentives, and give more attention to the role of local universities in technology diffusion and technology application.