Abstract: The cross-border innovation of emerging technologies has promoted the trend of the cross-border integration in the internal knowledge network. This paper analyzes the evolution of the knowledge flow path and the structural characteristics of an emerging technology knowledge network with the development of cross-border integration based on the patent data coming from DII (Derwent Innovation Index), which targets the field of virtual reality technology and uses social network analysis method as well as patent citation network.The results show that the emerging technology knowledge flow path evolves from one-way path to mixed path to two-way path, and the continuous increase of both core and peripheral enterprises widens the development space of the two-way path.The number of knowledge fiow path has increased sharply and the direction of that has dispersed,which leads to the emergence of the cross-border integration of knowledge networks between enterprises and regions. And the cross-border integration is characterized by increased heterogeneous knowledge, flexible knowledge connection and expanded network scale.The central enterprises and central regions further strengthen the cross-border integration capacity through the knowledge flow preference of "Central regions cite the domestic knowledge and non central regions cite the knowledge in central regions",reflecting obvious first mover advantages.