Abstract: Social innovation is an effective way to solve social problems such as poverty, environmental pollution and the aggravation of polarization between the rich and the poor. Although social innovation is as important as scientific and technological innovation, its mechanism of transformation and practice is more complex, which requires the exchange and cooperative production of knowledge producers and knowledge users. Knowledge mobilization can break through the "barriers" among knowledge subjects, effectively connect knowledge producers and knowledge users, change the situation of "going their own way" between knowledge subjects, and improve the level of social innovation. The existing literature on knowledge mobilization and social innovation is fragmented and scattered in different research fields. Based on 224 literatures from 2007 to 2020, this paper systematically combs the conceptual framework, operation mechanism and evolution paradigm of knowledge mobilization, discusses the relationship between knowledge mobilization and social innovation based on the four helix theory, and constructs a theoretical analysis framework of knowledge mobilization from the perspective of social innovation, so as to provides theoretical guidance for bridging the gap between theory and practice of social innovation and effectively promoting the achievements transformation of social innovation. The results show that knowledge mobilization is different from the traditional one-way transfer and linear transmission of knowledge, but the two-way interaction and knowledge sharing between knowledge producers and users. Knowledge mobilization is a complex system composed of knowledge producers, knowledge users, knowledge intermediaries and their situations. Knowledge mobilization includes four modes: producer pull, user push, knowledge exchange and knowledge cooperative production. It has experienced the evolution from linear model to circular iterative model. Its operation mechanism is a circular iterative process including research, dissemination, utilization and influence. In this process, the public is embeded into the social innovation system, forming an innovation ecosystem including the government, universities, enterprises and the public. Different knowledge subjects constantly exchange and interact with each other to promote the co-production of knowledge and produce the value increase.