Abstract: TRIZ theory plays a crucial role in building collaborative innovation system. Based on refining and sublimation of TRIZ theory, this paper explored the characteristics and conditions of the construction of collaborative innovation system oriented to TRIZ of enterprise internal. Selecting seven companies which applied TRIZ to build collaborative innovation system obtaining great success and became the model enterprises of innovation method in Hubei for multiple cases studies and using T-LAB9.0 analysis software, this study got six key point and four thematic elements of TRIZ oriented the construction of collaborative innovation system of enterprise internal, and verified the possibility and reality of the system construction.