Abstract: Under the context of innovation drives development strategy, the competitive strategy of enterprises depend more and more on their innovation ecosystem. As the third organizational form between market and hierarchy, the ecosystem perspective becomes the new direction of innovation research paradigm. Current research lacks the theoretical analysis and evolution descriptions of innovation ecosystem theory systematically. The paper discusses the origin, knowledge evolution and theoretical framework of innovation ecosystem theory under scientific metrology. The results indicate the main researches of innovation ecosystem focus on four clusters referred to “business ecosystem”, “value creation”, “open innovation”, “Innovation Ecosystems”. On the basis of the core researches analysis, the complete knowledge view of innovaion ecosystem research evolution is composed of three dimensions of core literature, theoretical foundation, and research methodology.