Abstract: Disruptive innovation plays a significant part in driving industrial development. We investigate the role of technological regimes in the influence of disruptive innovation on industry evolution in terms of technological opportunity and appropriating condition. Results find that with more opportunities and lower appropriate condition, the disruption is speeding up, firms’ average age tends to be lower, and market shares of incumbent firms and number of survival incumbent are becoming smaller. This paper provides reference for firms to allocate their resources properly and for government to implement some relevance policies according to technological regimes.