Abstract: The transformation and upgrade of manufacturers require sustained radical and incremental innovation dynamics. A case study is done by analyzing JMC’s continuous breakthrough period, structural mechanism period and flexible mechanism period through multiple methods, in which we find out by comparison that leadership mechanism has difficulty in generating core innovative competencies, and structural isolation mechanism may lead to large coordination costs and unit rigidity, while the cross-level flexible mechanism, e.g. including ambidextrous culture, contingent leadership and ambidextrous employee mental models, can be transformed into sustained ambidextrous innovation dynamics. This article has explored the interactive relations among the antecedents of ambidexterity through case analysis. It also has expanded the boundary of ambidextrous culture and mental model theories. The conclusion offers guidance to better innovation and upgrade of Chinese manufacturers.