Abstract: The emergence of the platform model has provided a new direction for the development and transformation of major SMEs. Taking the platform-oriented enterprise as the research object, using the system dynamics method, the business model innovation system is comprehensively analyzed, and then the platform-based enterprise business model innovation system dynamics model is constructed. Based on the rapid development of online tourism in recent years and the accessibility of data, the online travel platform, Ctrip.com, was selected as a simulation case to verify the validity of the model, and then perform a composite simulation and sensitivity analysis on the model. The result indicates that big data ability, bilateral market benefit coefficient, and service quality coefficient and diffusion factor are the key drivers affecting the performance of platform business model innovation system.